NOLVADEX









Product Name
Nolvadex 20mg
Active Ingredient
Tamoxifen as Citrate
Manufacturer
Astrazeneca
Product Type
Post Cycle Therapy (PCT)
Product expiry date we are currently shipping
Jan 2018

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Nolvadex 20mg


Nolvadex is the name of the drug whose scientific name is tamoxifen citrate. Nolvadex is not a steroid - it is a potent anti-estrogen used as an ancillary drug during cycle when symptoms of gyno occur. It can also be used post cycle to restore natural testosterone production. Symptoms of gyno can occur when using a cycle which contains drugs which aromatize, including (but not limited to) testosterones such as enanthatecypionate, and suspension. The drug is an estrogen agonist / antagonist, which binds to estrogen receptors in different tissues. Whether nolvadex acts as an estrogen agonist or antagonist depends on which type of tissue it is working in. When the tamoxifen molecule binds to the receptors, estrogen is blocked and cannot result in any type of action - therefore an anti-estrogen effect is exhibited. Nolvadex is used clinically in the treatment of breast cancer since many forms of breast cancer are responsive to the action of estrogen. Nolvadex blocks its actions and works as an effective treatment. Aside from direct treatment of breast cancer, it is used as a preventative measure for those with a genetic predisposition for breast cancer. While nolvadex is likely the most popular on-cycle anti-estrogen due to its affordable price, more potent remedies are avaialable such as arimidex, femara, and aromasin. These ancillary drugs prevent estrogen from being manufactured in the first place and make gyno related side effects virtually nonexistent. 

There is an enzyme in the male body known as aromoatase which is capable of altering testosterone so that it forms estradiol - an estrogen derivative. Estrogen is structurally similar to testosterone and it is present in the male body, but to a much smaller extent than testosterone. Since aromatase can aromatize manyanabolic-androgenic steroids, increased levels of estrogen can be a concern for the on-cycle bodybuilder. These levels can cause side effects, the main one being gyno (the development of female breast tissue in men). Symptoms that gyno is developing are itchy nipples, swelling or a small lump under the nipple which is normally painful to the touch. If nolvadex is not on hand during cycle and this lump is left to develop, it can increase in size and may become impossible to get rid of in any method short of surgery. The surgery required for gyno is a simple procedure, but if this can be prevented in some way, most athletes would be willing to make the choices required to do so. High levels of estrogen also lead to an increased level of water retained in the body. The obvious result here is a loss in overall muscular definition - or that "bloated" look. This look is caused by the retention of subcutaneous fluid which will make the athlete look more smooth. Normally this is not a problem for the athlete bulking up, and preventative measures are not an important concern. As estrogen levels rise in the body, fat storage may also be increased. Estrogen is the main reason why women have a higher percentage of body fat compared to men. It is always a smart idea to have all ancillary drugs on hand, including anti-estrogenic drugs such as nolvadex, before commencing a cycle. For it symptoms occur during cycle, you may find that you are unable to obtain such drugs and from there, complications can arise. 

Nolvadex shows potential to increase production of follicle stimulating hormone (FSH) and lutenizing hormone (LH) in the male body which are both important to the enhanced athlete. This is the result of blocking the negative feedback inhibition caused by estrogen at the hypothalamus and pituitary. As a result, the hormones mentioned are released. Both clomid and cyclofenil also have this function. Nolvadex is also able to have an impact on an individual's level of serum testosterone. This is important for post cycle therapy when this testosterone stimulating effect is most beneficial. Nolvadex can help restore hormonal balance post cycle, which is also very important to the athlete. 

Either nolvadex or clomid can be used on-cycle as anti-estrogens and post-cycle to help normalize testosterone production quickly. HCG can provide an excessive level of stimulation to the testes, which has the ability to shock them out of a long state of inactivity. Generally HCG is not necessary in small cycles where dosages are kept low. However, it will help normalize things faster than if it is not used, so many choose to run it on-cycle for this added benefit. 

A standard dosage of nolvadex on cycle as an anti-estrogen would be 10-30mg a day. The amount used would depend on what effect the user would like to elicit. More would clearly elicit a stronger effect, but users should determine how much they will require by starting at lower dosages and working their way up, so as not to use more than they require for the desired effect. For those steroid users who are using highly aromatizing substances (such as testosterone suspension), or those who have a sensitivity to estrogen, using nolvadex during cycle will probably be a smart idea to start early in the cycle. 


FURTHER INFORMATION

Nolvadex general information


STACKING AND USE
If problems of gyno show up during a cycle, the use of 20-30 mg of nolvadex should take care of the problem, and this quantity of nolvadex should be used until several days after symptoms subside just to be safe. 100mg of clomid, the weaker counterpart of nolvadex, can also be used to contain these problems. Using anti-estrogens or aromatase inhibitors during cycle will reduce your gains, so they are not recommended to use concurrently unless gyno or estrogen related symptoms show up. Exceptions to this are for users who are highly sensitive to estrogen (for example those with a genetic predisposition to gyno), or those using highly aromatizing substances. 

Once a cycle of steroids is finished, post cycle therapy should always be included in order to bring back normal levels of testosterone production which have been suppressed for the length of the cycle. If only oral steroids were used, post cycle therapy should start immediately. If short acting esters or water based injectables were used, PCT should start within 4-7 days after the last injection was made, and if longer acting esters were used, PCT should start 1.5-3 weeks after the last injection (depending on the specific steroid). The length of PCT normally runs between 3-5 weeks. The general rule of thumb is that the longer acting the product cycled was, the longer the therapy should be. When used properly, nolvadex can help the athlete regain natural production and normalize all other factors fairly quickly. Doses of both clomid and nolvadex are tapered down. 

Standard Nolvadex Post Cycle Therapy 

Week 1 (or 2): 40-50 mg of nolvadex daily. 
Week 2 (or 3) - Week 4 (or 5): 20-25mg of nolvadex daily. 



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